En efecto, tanto Roxy como Poison fueron originalmente concebidas como hombres por Capcom. Una historia muy enrevesada la verdad, pero eso no quita que el dibujo sea genial, y siempre nos queda la regla 63 para "ellos" ^^U
No. This is Roxy which was created just to be a palette swap enemy but was given her own back story. Officially Roxy is a female, and always has been. Poison however is the one that is ambiguously kept questionable but lean's towards being a guy who cross dresses based on story elements, and even dialogue from the character's.