I'm surprised Sweet Tooth or Minion is not in this list. Well, perhaps Twisted Metal doesn't count because it contains a variety of different people, from social misfits to joyriders.
I don't consider Twisted Metal a series with villains. The only one that could be a villain is Calypso. A villain that I could've put on here was "The Box Ghost" from Danny Phantom but he's more of a goofy/gag character.