I love how much this is feelinglike a frame from a traditional media manga! The black and white you've got so far on the coat is looking really great! And that hair. Oh man. You've got your work cut out for you with how much is remaining, but so far it is looking really good. (:
I like the folds you have going on the pants, they read really well. Around the knees seems a little off though, the wrinkles don't seem to fold around any knee caps, and the lower legs/calves don't look like the attach quite right.
Her right hand is looking pretty good for the most part! I think that hear actual palm is a bit short, and the wrist could use a little definition though.
Regarding the face, I know this might be a stylistic choice but I'll throw this out there. I think the eyes are a bit wide set. That would be a very easy fix to just test out in Photoshop though. I also think the nose and especially the mouth are proportionately small, but again that could be a style choice.
Over all really good though! I am very interested in seeing the finished piece. (: