We'll see how things go but, personally, I'd prefer that the writing & animation teams involved buck the 'reboot'/'remake' trend and make a more original series.
MTV struck more than gold during the 90s with shows like Daria, Downtown and The Head. If this new MTV Studio isn't planning to follow Daria (among other characters) during her college years, I'd prefer that they use what they learn from the aforementioned (UNCUT) episodes as a cornerstone to a better (read: weirder) show.
*Anything* is possible in the world(s) of anime-tion. A show about
- amateur superheroes (ie a shapeshifting goth girl, a dominatrix with zipper-based powers, etc)
- a youkai rock band
- a college student and her (shameless) female genie
- sentient techno-organic/robot women learning about human behaviour (via strip clubs, etc)
- all of the above
could do more than upstage classic cartoons like Duck Amuck and the Teen Titans episode, Fractured - it could raise the bar on what the team(s) and medium are capable of.
Here's hoping that MTV will consider these other possibilities.
Until then, let's judge the final product on its own merits, once/if it arrives.