I recently found your work and love these pieces that are open for interpretation.
Here are two interpretations that I saw when I observed this piece:
The two wolves are old friends/lovers of the girl and care for her, to the point of being possessive. However, she has left both of them, at separate times, and now has become enchanted by a new guy. Both of her old lovers suspect that this new person will not treat their loved one like they still want to, and may be even be a danger to her. They are struggling to understand why she cannot see this, and how she is blinded by her attraction to this man. The two who care for her can only feel betrayed.
The locket that they girl holds contains two images. The one that lies discarded and in the shadows is a picture of her two brothers, one older than the other, shoulder to shoulder, smiling out at her. However, she no longer looks at this image of her family that cares for her and instead looks into the other half of the locket, which is a mirror. In it, she is impressed and satisfied with how she appears. Her brothers, looming behind her, watch helplessly as she becomes self absorbed. Her younger brother, the one at the top right, is angry at her for becoming this way, losing her kindness and generosity. Her older brother is angry as well, but also feels sadness as he doesn’t believe he can help his little sister. The color of the brothers’ blue eyes, juxtaposed with their sister’s orange eyes, further express the boundaries she’s created between herself and her family and how she views herself above them.