The Avengers of Earth 357, known as the Paladins are a S.H.I.E.L.D sanctioned superhero team.
Nick Fury is a moniker passed down from director to director at S.H.I.E.L.D. The current Nick Fury is a woman of Arabic descent.
The Spider-Man of this universe is Rowan Erikson, an agent of S.H.I.E.L.D’s elite S.T.R.I.K.E team under the codename Agent Spyder who would then join the Paladins then go for a solo career.
Bullseye, real name Lester Fletch, is Agent Spyder’s partner, acting as spotter and sniper.
Captain America is Peggy Carter instead of Steve Rogers, who in a cruel twist becomes the Winter Soldier.
The Hulk is Thaddeus “Thunderbolt” Ross rather than Bruce Banner.
Hercules and likewise all the Greek/Roman gods are the stand ins for Thor and the Asgardians.
S.H.I.E.L.D, or Testudo as it was known formed during the Roman Empire, as did the Phoenix organization (Hydra of Earth 616).
Phoenix (Hydra) was created after the fall of the Roman Empire caused by a Phoenix Force empowered Queen Boudicca. Their belief is that once a civilization reaches its zenith, it’ll fall into corruption shortly afterwards so they destroy it and from the ashes a new civilization will rise again
Tony Stark is in this reality an Antoinette “Toni” Stark, daughter of Anthony “Tony” Stark, a S.H.I.E.L.D agent.
The enemy of Toni Stark and larger villain in her story is Justine Hammer (Justin Hammer from Earth 616), her former business partner and friend.
Dr Otto Octavius and Adrian Toomes (Doc Ock and the Vulture of Earth 616) are in this reality S.H.I.E.L.D scientists.
Venom, along with three of its four offspring were killed, leaving only one Symbiote called Ravage.
Rather than striking what would be Wakanda, the vibranium meteorite struck Atlantis instead, causing it to become a vastly technologically advanced civilization.
Hank Pym, Janet Van Dyne, and Reed Richards (Ant-Man, the Wasp and Mr Fantastic of Earth 616) are AIM scientists.
Mysterio, real name Quinn Beck, is a S.H.I.E.L.D sanctioned hacker and intelligence operative.
Victoria Domashev aka the Witch Queen of Latveria (Victor von Doom aka Dr Doom of Earth 616) is an ally of S.H.I.E.L.D, the mother of Pietro, Wanda and Lorna (Quicksilver, the Scarlet Witch, and Polaris) and married to Erik Lehnsherr (Magneto), who is both an ambassador for mutant affairs and the leader of an Xavier School for the Gifted type institution.
Natasha Romanov (Black Widow of Earth 616) is the loyal bodyguard of the Latverian Royal Family.
Latveria is a safe haven for mutants and other oppressed minorities.
Symkaria doesn’t exist in this world and where it would be is more Latveria.
Silver Sablinova (the Silver Sable) and her Wild Pack are a special forces squad for Latveria.
Vision in this reality is the villain, created by AIM originally as an advanced artificial intelligence computer to aid them while conversely Ultron is the hero.
Johnny and Susan Storm (the Human Torch and the Invisible Woman of Earth 616) were a pair of daredevils who currently moonlight in separate careers as a professional thief (Susan Strom) and assassin (Johnny Storm).
Firefist (Russell Collins) is a mutant supremacist and leader of the Brotherhood of Mutants.
Peter Parker and Gwen Stacy are married, scientists at Stark Industries and run a foster home.
Juggernaut, Colossus and Power Man(Cain Marko, Piotr “Peter” Rasputin and Luke Cage) are cage fighters and muscle for hire.
Domino (Neena Thurman) is the head of an underground gambling syndicate.
Natalia Essex (Nathaniel Essex aka Mr Sinister of Earth 616) is an insane geneticist and surgeon obsessed with creating “perfect mutations.” To that end she kidnaps people and tries to force their X gene or surgically alter them. Those with undesirable mutations or who can’t mutate are killed and dumped.
Hawkeye (Clint Barton of Earth 616) is a freelance assassin, often in competition with Johnny Storm.
Thanos is more of a scientist/warrior, emphasis on scientist.
Mary Jane Watson is the leader of a female rock band known as The Mayday’s.
Max Dillon (Electro of Earth 616) is an EDM artist under the stage name Electro.
After Vision goes rogue from AIM, he is replaced with an artificial sentience dubbed MODOC (Mechanical Organism Designated for Optimal Conquest)
Ravage eventually gives birth to a new symbiote, dubbed Malice which is bonded to an abused dog.