I came up with this idea at one of those random times of night when inspiration hits randomly and at high speed; unfortunately inspiration has no insurance which can cause problems. The basis of the story if fairly simple: Before the time of the great flood the world had magic. So what do I mean by that... well everything take the standard Dungeons and Dragons and you've got the idea. I digress, ah the box, the box is the physical manifestation of the separation between our world and the same world with magic.
So that tells you the basics of the world, now for the actual story. I don't have any characters yet but this is the storyboard:
Act 1: Discovery
The dark side of the moon: astronauts find the box while setting up an unmanned observatory. Accompanying the box is a tome, in remarkably good condition, which explains the history of the box. The tome essentially says that Pandora rather than opening the box to unleash chaos on the world actually was the one to close it.