EDIT: From Nintobervilltch 2008, the progenitor for my annual Nintober project. Back then I only sketched 11 Nintendo villains rather than 31 monsters. It's 2012 and I'm redoing the old artwork and dragging them into the new template to make it one continuous project, if you like!
Bio computer? Meaning she is partially organic. She's called "Mother brain".. Would this mean she could've once been a part of or have been a regular living organism? Pherhaps humanoid? Either way she's downright disturbing and frightening to look at. Props to Samus for going tou to toe with this fright-show.
I remember you had to be extra careful not to lose a lot of health during the fight with Super Metroid's MB; she tends to fire two of those omega beams if you're still relatively alive and kicking, accidentally killing you with the second beam.
Maybe "Fusion" just seemed easier to me, 'cause I played through Super Metroid so much. (I did like the new feature of being able to hold onto ledges, which lead to some clever platforming in the game.)