I'm afraid the Minbari are toast here. Their ships may be powerful, but they're unshielded, and comparatively slow. I don't think their weapons are anything new to the Borg, either, so they wouldn't even get a first strike advantage the way the Enterprise did. The Shadows, or Vorlon, might do better.
I always hear a lot of talk about warp/hyperdrive, and phasers/turbo lasers. But what a lot of people forget about these fights is that the Empire likes to use ion cannons to disable vessels. We know Star Trek tech used to be vulnerable to ion radiation, because it happened all the time in TOS when they would accidentally get caught in an ion storm. It wasn't such a thing in TNG, but maybe because their shields were better and able to weather such storms, or their navigation was better, so they just avoided them.
But even if TNG doesn't have to worry about natural ion storms anymore, an Imperial ion cannon is not natural. They're weapons designed to take out ships, and I'm willing to bet they'd be a real threat to the Enterprise D.
In any case, I love this picture. It would be a fun fight to watch