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The Binding of Isaac by DrManiacal The Binding of Isaac by DrManiacal
EDIT: Recently I made a new updated version of this for Rebirth, check it out here:…

I picked this game up a couple weeks ago, and it has REALLY surprised me so far. Who knew that playing as a 5 year old boy running away from his insane murderous mother through a horrible labyrinth under his house with his tears as his only means to defend himself could be so fun!

Here are the different playable characters (from right to left: Judas, ???, Maggie, Isaac, Cain, and Eve) and some of my favorite bosses (Thanks to Iketsu for the idea regarding how the bosses would play into this composition). I tried to illustrate the characters sort of how I like to play them. Judas I keep the book of belial and go for as much damage as possible, I like to utilize Maggie's yum heart and get really bulky with lots of health, with Isaac I make the most of the D6 and get amazing builds nearly all the time, Cain I like to get as many pills as possible and Mom's pill bottle if it drops to make good use of his luck foot, Eve is fun to get really low health on with a bunch of spirit hearts to stay in her cursed form constantly, and ??? is just dead on the floor with poop everywhere because that is what I do with him most. Poop everywhere and then die. Though I actually have the second most number of successful runs using him, go figure.

ANYWAYS this was fun, if you haven't heard of the game definitely check it out on steam.
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SuperMarioFan65 Featured By Owner Jul 1, 2017  Student Digital Artist
Awesome work
OverMaxedOut Featured By Owner Sep 24, 2016  Hobbyist Digital Artist
This is awesome. It has the same feel like it was truly made for the game, though Cain looks like he's going to have a heart attack Jesus Christ
Moms-heart Featured By Owner Sep 1, 2016
Amazing art! Would you custom make a piece for me? For a birthday card?
DrManiacal Featured By Owner Sep 2, 2016  Professional Digital Artist
Hey there! I'm always happy to take on commission work. If you're interested send me a note here or email me at with what you have in mind, and we'll work something out!
trashtale Featured By Owner Jun 1, 2016  Student Artist
This is amazing
MrPicklesHtf Featured By Owner Jan 11, 2016  Hobbyist Artist
It is a great game.
And your artwork looks awesome!
DrManiacal Featured By Owner Jan 12, 2016  Professional Digital Artist
hah, thanks! It's hard for me to look at this old piece as awesome nowadays though. I redid this one last year sometime if you haven't seen it, and I'm a bit happier with it lol.
ThereallylargeFly Featured By Owner Sep 18, 2015
I love the expressions!
Carniforous Featured By Owner Aug 6, 2015
this is amazing art.
DrManiacal Featured By Owner Aug 9, 2015  Professional Digital Artist
Thanks! Haha looking back on this, amazing isn't the word I would use to describe it personally. But I certainly appreciate the compliment. <3
Carniforous Featured By Owner Aug 15, 2015
It's honestly the best I've seen. No joke. It's my background.
Ajax94 Featured By Owner Jun 24, 2015
This is a fantastic art! :D
daijathewolf Featured By Owner Nov 27, 2014
PrawnM Featured By Owner May 25, 2014  Hobbyist Digital Artist
DrManiacal Featured By Owner May 26, 2014  Professional Digital Artist
Thank you!
Skagzilla Featured By Owner Apr 25, 2014
I did NOT expect to see champion bosses in fanart. (Green Duke)
BloodSoacker Featured By Owner Mar 11, 2014  Student Artist
Really great work
Mr-Illusionist-1331 Featured By Owner Mar 7, 2014  Student General Artist
Amazing, well done:)
flandre495 Featured By Owner Jan 26, 2014  Student General Artist
Cain: :iconpillshereplz:
tidus1998 Featured By Owner Oct 28, 2013
what program use to make this?
widowman321 Featured By Owner Oct 23, 2013
u forgot samson and the 20face dice
Foxeater2 Featured By Owner Sep 27, 2013  Student General Artist
this... is... perfect....
The-Orange-Cow Featured By Owner Sep 2, 2013
Great art!
Derethar Featured By Owner Aug 16, 2013
i.. must give all my favourites.. i must.. download.. i must.. PRINT AND PUT IT ON MY WALL!!

its just.. beautiful.. both the game and this paint.. <3333

just take my favs.. all of them!!!
kuuro666 Featured By Owner Nov 2, 2013
You said what I can't say but feel. ^^
heysonyablade Featured By Owner Aug 10, 2013  Student Interface Designer

Hello, DrManiacal, someone STOLE this srtwork form you and posted it on Steam.

You should take a look:…


inuyasha1167 Featured By Owner Aug 4, 2013  Hobbyist Artist
awesome drawing omg so cool.
Plegathion Featured By Owner Jul 22, 2013
hey I just thought I should let you know someone posted this on steam try to pass it off as their own 
slender12 Featured By Owner Jul 1, 2013  Student Photographer
this is epic
Flandre-Hime Featured By Owner Jun 30, 2013
This is so cute! I love Isaac!
GrizzlySword Featured By Owner Jun 30, 2013  Professional
sorry for this, but you can send to Steam all you are think about this guy: [link]
decaffedgem Featured By Owner Jun 30, 2013  Hobbyist Digital Artist
Okay they may sound weird but...
when I saw this thumbnail, it kinda looked like a woman for awhile....

But it's a great picture. :D
King1cheetah Featured By Owner Jun 26, 2013
Amazing art pic and game :D
MantlegenG Featured By Owner Apr 15, 2013  Hobbyist Writer
Epicness... My two best favorite is Judas and Eve
TheCharleyJay Featured By Owner Apr 5, 2013
LIEK OMG U FORGOT SAMSON WHYYYYYYYY :angered: :nuu: :angered:

Now that that's out of the way, is it bad that I found Cain's obsessive pill-eating and ???'s hopeless demotivation absolutely hysterical?

It's funny because of the seriousness. For a game that's so cartoony and funny, it's also incredibly dark, disturbing, complex, and biblical. Or maybe the horribleness is why it's so funny. Anyhow, putting Larry's body across the bottom of the page was a good choice; it negated an awkward eyes-strolling-off-the-page. The lighting is very good, and I love how Isaac is above the others, right in the middle with the most light on him. His face and angel outfit strike out to me as a id who just goes way through much while also being naked. It's even worse because the other playables look suspiciously like Isaac dressing up as different Bible characters. I think his pain in this picture is the reason why I found Cain and ??? so funny. :U
DrManiacal Featured By Owner Apr 9, 2013  Professional Digital Artist
Yeeeeah sorry I didn't actually have wrath of the lamb when I made this, so that's why samson isn't there. :(

Thanks for your thoughts, and yeah the game is certainly fascinating because of that unique feel you described. That and the replay value; so simple yet so complex and engaging at the same time. I gotta go boot it up again sometime hehe.
TheCharleyJay Featured By Owner Apr 9, 2013
I didn't realize Samson was an expansion. I thought that was just Eve. Well, Samson's a really interesting playable, especially if he gets extra health. I don't really like using Eve that much. "Whore of Babylon" is always dramatic but if you get it with her, it's pretty much a guarantee you're going to lose.
homestuckWizard Featured By Owner Mar 31, 2013
The duke of flies is all like :iconlolwutplz:
DrManiacal Featured By Owner Apr 1, 2013  Professional Digital Artist
oh my , the resemblance is uncanny.
homestuckWizard Featured By Owner Apr 19, 2013
It's even green.
homestuckWizard Featured By Owner Apr 1, 2013
Oh my, the sarcasm is ridiculous.
superstripey87 Featured By Owner Mar 25, 2013
whoa..... AWSOME!
Railrugs Featured By Owner Mar 15, 2013
This is some great stuff! Judas looks so badass, and I love Cain's frantic pill munching. If you've ever gotten Mom's Bottle of Pills with Cain, the game gets much easier. Happened to me once.
Artich0ker Featured By Owner Feb 12, 2013  Hobbyist Digital Artist
wow Eve looks so badass XD Maggy ate the bucket of lard?
Dragmoore Featured By Owner Jan 27, 2013
My new mobile phone wallpaper, thank you very much! I love this game and this style is great.
DrManiacal Featured By Owner Jan 31, 2013  Professional Digital Artist
Yeah same here, can't wait for the remake!
ANDREU-T Featured By Owner Jan 12, 2013
Awesome =D
Shoukana Featured By Owner Jan 4, 2013  Hobbyist General Artist
Thank you for including Eve and Cain, my two favorite characters! :D
HeartlessVulpes Featured By Owner Dec 26, 2012
Wow, great picture!

I have played this game too and it really fascinated me.
The levels are very difficult. Especially the boss fights I think.

In fact I love this game and this picture.
iloveyou520 Featured By Owner Dec 24, 2012  Hobbyist Artist
What a awesome picture you have draw,nice job :D
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Submitted on
July 30, 2012
Image Size
5.1 MB


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