Well when Dead Space came out it was probably one of the most scary games of its time. The game revolves around the main character Isaac Clark. Isaac is/ was an engineer and was sent with a recovery team to get the plant cracker USG Ishimora. The ship went dark so Isaac and the recovery team was sent to investigate. When they border the ship after nearly crashing the recovery ship into the hull of the Ishimora. Isaac has a side objective: find Nicole. Nicole was Isaacs girlfriend, maybe even his wife. While exploring the ship the team discovers what happened to the crew. They had been transformed into twisted unrecognizable versions of people, and the reason why this art reminds me of Dead Space is because the Necromorphs are designed after CAR CRASH VICTIMS! The things that you fight in the game are made because the developers thought that it would be a good idea to make the Necromorphs characters after car crash victims.
Just look up stuff for Dead Space. You'll find out just how f***ed up the game is. I can go into more detail but I think this is a good enough basis for you to get an idea about the game.