Original screencap: sta.sh/01kv7f1xi7hg
I've found this adorable anime called Shiawase Sou no Okojo-san, I can't believe how obscure it is. I strongly recommend it to everyone who likes cute and lighthearted anime, the humor is pretty decent too. ^^
I've been able to find just the first 17 episodes with English subs, but seems like the whole series is available in Japanese in youtube and it's easy to understand what's going on. XD No sign of the manga in the web though.
Okojo-san belongs to Ayumi Uno.