Dr. Will Rodman (James Franco) is developing a formula call AZ-12 which promises to repair cells in the human brain; a process which he promises will cure diseases like Alzheimer's Disease because his father Charles (John Lithgow) is suffering from it. Testing the formula on chimpanzees, a newborn baby chimp is saved from euthanasia and given to Will who quickly discovers the cure that was injected in the chimp's mother was passed on genetically and has thus boosted the intelligence of the ape whom he names Caesar (Andy Serkis).
8 years pass since then and Caesar's intellect has increased but Charles's condition has worsened, getting him heckled by a rude neighbor whom Caesar attacks to protect Charles. He is sent to an primate zoo where he quickly discovers the harsh reality and the cruelties of man, namely from a dick named Dodge (Tom Felton). But these cruelties push him to the breaking point as he decides it's time to stop this so he steals a m