Made and rendered with Blender 2.62 (Internal render, no Cycles)
Pretty much remade an old room of mine into this, then tested out lighting it with only internal lights...no sunlights or area lights coming through a window. Not as easy as I thought it would be, but it's my first attempt at it. Vignette, color curves, tiny bit of sharpening, all done in Blender's compositor.
Final version of my simple room scene, rendered in C4D with global illumination. Many special thanks go out to my friend ~Doggnchris who helped me out immensely with the lighting. Thanks Chris! Please go check out his gallery, he has some amazing things, including this one: